BiochemistrybioRxiv
Molecular basis of VEGFR1 autoinhibition at the plasma membrane
M. P. Chakraborty, D. Das, P. Mondal…·R. Das
This study identifies a mechanism by which VEGFR1 remains constitutively inactive through juxtamembrane inhibition and phosphatase activity, explaining its differential regulation compared to VEGFR2.
DOI 10.1038/s41467-024-45499-2