A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells
P. Mondal, G. Alyateem, A. V. Mitchell, M. M. Gottesman
bioRxiv · Feb 15, 2024 · PreprintCancer Biology
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P. Mondal
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2019-2024 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 6 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship8 papers
Recent·Most cited
Development of non-sedating antischistosomal benzodiazepines
M. Y. Mian, D. Sharmin, P. Mondal, J. B. Belayet, M. M. Hossain, P. McCusker, K. T. Ryan, A. Y. Fedorov, H. A. Green, S. S. Ericksen, M. Zamanian, V. V. N. Phani Babu Tiruveedhula, J. M. Cook, J. D. Chan
This paper develops non-sedating antischistosomal benzodiazepines by modifying meclonazepam's structure, identifying compounds effective in vivo with reduced sedation.
bioRxiv · Jan 26, 2024 · PreprintPharmacology & Toxicology
Molecular basis of VEGFR1 autoinhibition at the plasma membrane
M. P. Chakraborty, D. Das, P. Mondal, P. Kaul, S. Bhattacharyya, P. K. Das, R. Das
This study identifies a mechanism by which VEGFR1 remains constitutively inactive through juxtamembrane inhibition and phosphatase activity, explaining its differential regulation compared to VEGFR2.
bioRxiv · Jun 8, 2023Biochemistry
Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance
N. Zutshi, B. C. Mohapatra, P. Mondal, W. An, B. T. Goetz, S. Wang, S. Li, M. D. Storck, D. Mercer, A. R. Black, S. P. Thayer, J. Black, C. Lin, V. Band, H. Band
This study shows that Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance by regulating the Akt-mTOR pathway.
bioRxiv · May 17, 2023Cell Biology
Arsenic induced alteration of neuroregulatory gene expression in Macrobrachium lamarrei: a neurotoxicological approach to grooming behaviour
C. Munshi, A. Mukhuty, A. Bandyopadhyay, A. D. Bhowmik, P. Mondal, P. Shaw, S. Bhattacharya
This study examines how arsenic trioxide affects neuroregulatory gene expression and induces autism-like behaviors in the freshwater prawn Macrobrachium lamarrei.
bioRxiv · Aug 30, 2022 · PreprintPharmacology & Toxicology
Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig
P. Mondal, N. Patel, K. Bailey, S. Aravind, M. A. Hollingsworth, A. J. Lazenby, M. A. Carlson
This study induces and characterizes pancreatic tumors in Oncopigs to create a large animal model of pancreatic cancer with molecular features similar to human disease.
bioRxiv · May 29, 2020Cancer Biology
Hyperinsulinemia promotes HMGB1 release leading to inflammation induced systemic insulin resistance: An interplay between pancreatic beta-cell and peripheral organs
A. Choubey, A. K. Kar, K. Girdhar, T. Chattopadhyay, S. Dogra, S. Kushwaha, B. Medhi, A. Bhansali, C. K. Mantri, U. K. Seetharam, D. Ghosh, P. Mondal
This study shows hyperinsulinemia promotes inflammation via HMGB1 and TLR4 signaling, leading to systemic insulin resistance, and demonstrates naltrexone's protective effects.
bioRxiv · Jul 17, 2019 · PreprintPhysiology
Repurposing protein degradation for optogenetic modulation of protein activities
P. Mondal, V. V. Krishnamurthy, S. R. Sharum, N. Haack, K. Zhang
This paper introduces GLIMPSe, a light-modulated protein stabilization system that controls protein levels in live cells without requiring target-specific engineering.
bioRxiv · Jun 23, 2019Bioengineering