Crystal structure of full-length cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication
P. Chaoprasid, P. Lukat, S. Mühlen, T. V. Heidler, E. M. Gazdag, S. Dong, W. Bi, C. Rueter, M. Kirchenwitz, A. Steffen, L. Jansch, T. Stradal, P. Dersch, W. Blankenfeldt
The paper determines the crystal structure of CNFY, revealing domains involved in toxin translocation and identifying its potential as a drug delivery tool.
bioRxiv · Apr 7, 2020Biochemistry