Semaphorin3F reduces vascular endothelial and smooth muscle cell PI3K activation and decreases neointimal plaque formation
C. Rattanasopa, D. Castano Mayan, C. Su, A. J. Farrugia, M. Corliano, P. Nilcham, C. Pang, M. Hota, S. M. Koh, W. W. Lee, D. M. Cibi, A. Aiba, M. K. Singh, S. C. Wong, O. Rotzschke, , R. R. Singaraja
This study shows that Semaphorin3F reduces PI3K activation in vascular endothelial and smooth muscle cells, leading to decreased neointimal plaque formation and increased plaque stability.
bioRxiv · Mar 22, 2022 · PreprintPhysiology