P. Ranjan

Guggulsterone Enhances NKX3.1 Expression and Induces Apoptosis in Prostate Cancer Cells: Implications for Chemoprevention

This study shows Guggulsterone induces apoptosis in prostate cancer cells by increasing NKX3.1 expression and stabilizing its mRNA and protein, suggesting it as a potential chemoprevention target.

Discovery & Evaluation of novel fluorescence molecules for selective recognition of G-quadruplexes structure

This study identifies and evaluates novel chroman derivatives and their borondifluoride complexes as selective G-quadruplex binders through in vitro and cellular assays.

Discovery of novel G-quadruplex stabilizing compounds from medicinal plant & Evaluates their cellular toxicity

This study identifies two non-toxic G-quadruplex stabilizing compounds from medicinal plants and evaluates their cellular toxicity.

Calcimycin mediates apoptosis in Breast and Cervical cancer cells by inducing intracellular calcium levels in a P2RX4-dependent manner

This study shows calcimycin induces apoptosis in breast and cervical cancer cells by increasing intracellular calcium levels via P2RX4 and p38 MAPK pathways.

A cytoplasmic protein kinase in Chlamydomonas couples engagement of ciliary receptors to rapid cellular responses

The paper identifies GSPK as a cytoplasmic kinase that rapidly converts ciliary receptor engagement into a global cellular response by triggering cAMP increase and cell fusion in Chlamydomonas.

Microbial metabolism and adaptations in Atribacteria-dominated methane hydrate sediments

The paper investigates microbial metabolism and adaptations in Atribacteria-dominated methane hydrate sediments, identifying key metabolic pathways and stress responses.