P. Reis

The study of hormonal metabolism of Trincadeira and Syrah cultivars indicates new roles of salicylic acid, jasmonates, ABA and IAA during grape ripening and upon infection with Botrytis cinerea

This study compares hormonal metabolism in two grapevine cultivars during ripening and infection, finding differences in ABA, IAA, and jasmonates that correlate with resistance to Botrytis cinerea.

Beyond members of the Flaviviridae family, sofosbuvir also inhibits chikungunya virus replication

This study shows sofosbuvir inhibits chikungunya virus replication in cell cultures and animal models, with selectivity over ribavirin and efficacy in vivo.

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

This study shows that sofosbuvir inhibits Yellow fever virus replication in vitro and protects mice from infection, suggesting it as a potential therapeutic option.

Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequela

This study shows sofosbuvir reduces ZIKV levels and improves survival and long-term memory in infected mice.