ABHD11 regulates 2-oxoglutarate abundance by protecting mitochondrial lipoylated proteins from lipid peroxidation damage
P. S. Bailey, B. M. Ortmann, J. W. Houghton, A. S. H. Costa, R. Antrobus, C. Frezza, J. A. Nathan
The paper identifies ABHD11 as a mitochondrial hydrolase that protects lipoylated proteins from lipid peroxidation, thereby regulating 2-OG levels and 2-OG DD function.
bioRxiv · Apr 18, 2020 · PreprintCell Biology