Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors
P. Sam, E. Calzada, M. G. Acoba, T. Zhao, Y. Watanabe, A. Nejatfard, J. Trinidad, T. Shutt, S. E. Neal, S. M. Claypool
The paper investigates the subcellular localization of Psd1 and shows that impaired phosphatidylethanolamine metabolism triggers an ER-assisted response to resolve nonfunctional mitochondrial precursors.
bioRxiv · Dec 10, 2020Cell Biology