S. E. Neal

This study identifies a novel ERAD-independent role for Dfm1 in sphingolipid homeostasis by regulating Orm2 export and degradation.

The paper identifies a chaperone function of Dfm1 in resolving misfolded membrane protein stress in yeast, independent of Cdc48 and distinct from its previously known role in protein dislocation.

This study uses csRNA-seq to identify transcriptional changes and regulatory elements during phase transition in Coccidioides immitis, revealing a WOPR homologue involved in pathogenicity.

This study identifies the mechanism by which derlin rhomboid pseudoproteases facilitate retrotranslocation of ER membrane substrates through substrate engagement and lipid thinning.

The paper investigates the subcellular localization of Psd1 and shows that impaired phosphatidylethanolamine metabolism triggers an ER-assisted response to resolve nonfunctional mitochondrial precursors.