Author

P. Shahi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. E. Royall· 2 shared A. M. Chrisman· 2 shared B. A. Adams· 2 shared D. B. Jaffe· 2 shared D. S. Reyes· 2 shared F. Tsai· 2 shared N. Raman· 2 shared P. M. Finnegan· 2 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. E. Royall

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Author profile →

3 papers

Recent·Most cited

Functional antibodies exhibit light chain coherence

D. B. Jaffe, P. Shahi, B. A. Adams, A. M. Chrisman, P. M. Finnegan, N. Raman, A. E. Royall, F. Tsai, T. Vollbrecht, D. S. Reyes, W. J. McDonnell

The paper shows that functional antibodies have a high probability of using the same light chain V gene, termed light chain coherence, unlike naive antibodies.

bioRxiv · Apr 23, 2022Immunology

enclone: precision clonotyping and analysis of immune receptors

D. B. Jaffe, P. Shahi, B. A. Adams, A. M. Chrisman, P. M. Finnegan, N. Raman, A. E. Royall, F. Tsai, T. Vollbrecht, D. S. Reyes, W. J. McDonnell

enclone computes approximate clonotypes from single-cell data, demonstrating high specificity with a probability of co-clonotyping unrelated B cells around 10^-9.

bioRxiv · Apr 21, 2022 · PreprintImmunology

Printed Droplet Microfluidics for on demand dispensing of picoliter droplets and cells

R. H. Cole, S.-Y. Tang, C. A. Siltanen, P. Shahi, J. Q. Zhang, S. Poust, Z. J. Gartner, A. R. Abate

This paper introduces a technology for high-throughput dispensing of picoliter droplets and cells with deterministic control, enabling precise array generation and integration of multiple measurement modalities.

bioRxiv · Jul 21, 2017Bioengineering