Spatial Clustering of CD68+ Tumor Associated Macrophages with Tumor Cells is Associated with Worse Overall Survival in Metastatic Clear Cell Renal Cell Carcinoma
N. H. Chakiryan, G. Kimmel, Y. Kim, A. Hajiran, A. Aydin, L. Zemp, E. Katende, J. Nguyen, N. Lopez-Blanco, J. Chahoud, P. Spiess, M. Fournier, J. Dhillon, L. Wang, C. Moran-Segura, , B. J. Manley
The paper quantifies cellular density and clustering of immune cells in metastatic ccRCC and finds that CD68+ TAM clustering with tumor cells correlates with worse overall survival.
bioRxiv · Jan 4, 2021Cancer Biology