Autonomous induction of hepatic polarity to construct single cell liver
Y. Zhang, R. de Mets, C. Monzel, P. Toh, N. Van Hul, S. S. Ng, T. Rashid, V. Viasnoff
This study shows that mature hepatocytes can autonomously polarize to form secretory hemi-apical lumens on bio-functionalized substrates, enabling controlled study of lumenogenesis.
bioRxiv · May 15, 2019 · PreprintCell Biology