Systems BiologybioRxivPreprint
Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis
George Rosenberger, Wenxue Li, Mikko M. Turunen…·Andrea Califano
The paper uses phosphoproteomic time-series data and the VESPA algorithm to analyze drug resistance mechanisms in colon cancer cells, revealing adaptive signaling rewiring confirmed by CRISPRko assays.
3 citations