In vivo bioreactor matures iPSC-CMs for MLP disease modeling
Sean A. Murphy, Gun-Sik Cho, Pattraranee Limphong, Dong I. Lee, Chulan Kwon
This study shows that in vivo maturation of MLP-KO iPSC-CMs recapitulates DCM phenotypes, while in vitro maturation does not.
bioRxiv · Aug 11, 2025 · PreprintBioengineering