NeurosciencebioRxivPreprint
Astrocytic PIEZO activation by heartbeat sound promotes extracellular matrix and maturation in human brain organoids
Alexandra Ferreira-Oliveira, Florian Rambow, Samira Rambow-Makhzami…·Egor Dzyubenko
This study shows that heartbeat sound activates PIEZO channels in astrocytes, promoting extracellular matrix synthesis and neural differentiation in human brain organoids.
DOI 10.1101/2025.10.21.683816