GenomicsCell GenomicsPeer-reviewed
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
José L. McFaline‐Figueroa, Sanjay R Srivatsan, Andrew J. Hill…·Cole Trapnell
The paper uses a combined single-cell genetic and chemical screening platform to analyze kinase dependencies in glioblastoma response to targeted therapy, identifying adaptive signaling and potential combination therapies.