Cell BiologybioRxivPreprint
Modeling ATN1 mutations in human iPSCs reveals early developmental roles of atrophin-1
Emilia Kozlowska, Natalia Ziojla, Bartosz Nowak…·Agnieszka Fiszer
This study generates an isogenic iPSC panel to investigate ATN1's role in human development and disease, revealing proliferation deficits and toxic gain-of-function effects in mutant ATN1 lines.
DOI 10.64898/2026.10.30.760413