Cancer BiologyPLoS ONEPeer-reviewed
Novel inhibitors of TTLL12s oncogenic potential that overcome suppression of ligation of nitrotyrosine to the C-terminus of detyrosinated a-tubulin
Amit Deshpande, Jan Brants, Christine Wasylyk…·Bohdan Wasylyk
The paper identifies two molecules that activate nitrotyrosine ligation to detyrosinated α-tubulin by targeting TTLL12, which suppresses this process, suggesting potential therapeutic applications for cancer and related pathologies.
7 citations