Author

Peter van t Hof

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:eQTL / molecular QTL mapping· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Albert HofmaniD· 2 shared Alexandra ZhernakovaiD· 2 shared André G. Uitterlinden· 2 shared Carla J.H. van der Kallen· 2 shared Coen D.A. StehouweriD· 2 shared Daria Zhernakova· 2 shared Diana van HeemstiD· 2 shared Ettje F. Tigchelaar· 2 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Albert HofmanORCID

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2 papers

Recent·Most cited

GenomicsNature GeneticsPeer-reviewedJan 1, 2017

Disease variants alter transcription factor levels and methylation of their binding sites

Marc Jan Bonder, René Luijk, Daria Zhernakova…·C

The paper identifies trans-meQTLs linking disease variants to methylation changes at transcription factor binding sites, revealing eight-fold more downstream effects than trans-eQTLs.

DOI 10.1038/ng.3721

humanDNA methylation

𝕏 PostBluesky

GeneticsNature GeneticsPeer-reviewedDec 5, 2016

Hypothesis-free identification of modulators of genetic risk factors

Daria Zhernakova, Patrick Deelen, Martijn Vermaat…·Dorret

The paper identifies context-dependent eQTLs in peripheral blood RNA-seq data from Dutch individuals using a hypothesis-free approach, revealing gene expression influenced by cell type and signaling pathways.

DOI 10.1038/ng.3737

humanbulk RNA-seq

𝕏 PostBluesky