BioengineeringbioRxivPreprint
Engineered AAV9 as in vivo gene delivery platform for the selective transduction of TME cell subsets
Muhammed Burak Demircan, Florian Straßheimer, Luca J. Zinser…·Christian J. Buchholz
This paper engineers AAV9 vectors to selectively deliver genes to specific tumor cell subsets, demonstrating efficacy in preclinical cancer models and clinical relevance.
DOI 10.1101/2025.06.11.658408