Molecular BiologybioRxivPreprint
Backtracking of influenza polymerase upon consecutive incorporation of nucleoside analogue T1106 directly observed by high resolution cryo-electron microscopy
Tomáš Kouba, Anna Dubánková, Petra Drncová…·S. Cusack
This study uses cryo-EM to observe how influenza polymerase backtracks after incorporating T1106-MP nucleotides, revealing structural changes that lead to chain termination.
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