Fibroblast mechanoperception instructs pulmonary developmental and pattern specification gene expression programs
Andrew E. Miller, Ping Hu, Rishi Bhogaraju, Riley T. Hannan, Daniel Abebayehu, Mete Civelek, Thomas Harrison Barker
The paper investigates how impaired mechanoperception in lung fibroblasts affects gene expression programs, revealing a link between integrin signaling and HOXA5 silencing in lung development and regeneration.
PLoS Genetics · Nov 10, 2025Peer-reviewedCell Biology