Author

Ping-Chung Chen

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:database / resource· 2 Approach:deep learning· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Xusheng Wang· 3 shared Anthony A. HighiD· 2 shared Gang YUiD· 2 shared Him K. ShresthaiD· 2 shared Huan Sun· 2 shared Jay M. YarbroiD· 2 shared Ju WangiD· 2 shared Junmin PengiD· 2 shared

Activity by Year

2016-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Xusheng Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell type-resolved proteomics reveals intra- and intercellular signalingin Alzheimers disease

Xue Zhang, Kaiwen Yu, Him K. Shrestha, Ying Zhou, Jiyuan Yang, Zhen Wang, Xiaokang Ren, Ping-Chung Chen, Huan Sun, Danting Liu, Yun Jiao, Jay M. Yarbro, Ju Wang, Zhiping Wu, Kiara Harper, , Junmin Peng

The paper presents a cell type-resolved proteomic atlas of Alzheimer's disease mouse models, identifying thousands of cell-specific protein changes and highlighting astrocyte-microglia signaling.

bioRxiv · Feb 4, 2026 · PreprintNeuroscience

Single Plaque Proteomics Reveals the Composition and Dynamics of the Amyloid Microenvironment in Alzheimer's Disease

Mengqi Chu, Ju Wang, Jay M. Yarbro, Ping-Chung Chen, Him K. Shrestha, Huan Sun, Mingming Niu, Zhen Wang, Sarah Harvey, Zhiping Wu, Yingxue Fu, Zuo-Fei Yuan, Tan Haiyan, Anthony A. High, Aijun Zhang, , Junmin Peng

The paper quantifies the proteomic composition of amyloid plaques in AD models and human brains, revealing stage-dependent remodeling and conserved proteins across species.

bioRxiv · Feb 4, 2026 · PreprintNeuroscience

Metabolome Identification by Systematic Stable Isotope Labeling Experiments and False Discovery Analysis with a Target-Decoy Strategy

Drew R. Jones, Xusheng Wang, Tim Shaw, Ji-Hoon Cho, Ping-Chung Chen, Kaushik Kumar Dey, Suiping Zhou, Yuxin Li, Nam Chul Kim, J. Paul Taylor, Udhghatri Kolli, Jiaxu Li, Junmin Peng

The paper introduces JUMPm, a formula-based algorithm for metabolite identification and false discovery rate estimation in metabolomics, validated on yeast and mammalian cells.

bioRxiv · Nov 26, 2016 · PreprintBiochemistry