Cell BiologybioRxivPreprint
Bronchoconstriction damages airway epithelia by excess crowding-induced extrusion
Dustin C. Bagley, Tobias Russell, Elena Ortiz-Zapater…·Jody Rosenblatt
This study shows that bronchoconstriction causes epithelial cell extrusion, leading to airway damage, inflammation, and mucus secretion, and that inhibiting extrusion prevents these symptoms.
DOI 10.1101/2023.08.04.551943