Author

Purva Khare

Duquesne University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Devika Soundara ManickamiD· 3 shared Balaji GovindaswamyiD· 2 shared Abigail SullivaniD· 1 shared Adithri Pingali· 1 shared Armen SaghatelyaniD· 1 shared Audrey Lawrence· 1 shared Baptiste LacosteiD· 1 shared Carol Milligan· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioengineering

Devika Soundara ManickamORCID

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Author profile →

3 papers

Recent·Most cited

Purinergic receptor activation rectifies autism-associated endothelial dysfunction

Julie Ouellette, Sareen Warsi, Phinea Romero, Purva Khare, Shama Naz, Leya Aubert-Tandon, Moises Freitas Andrade, Chantal A. Pileggi, Sozerko Yandiev, Joanna Raman‐Nair, James Yee, Nicole Blakeley, Balaji Govindaswamy, Cesar Henrique Comin, Mary-Ellen Harper, , Baptiste Lacoste

This study shows that purinergic receptor activation can correct endothelial dysfunction linked to autism in a mouse model by restoring bioenergetic function and cerebrovascular reactivity.

Neuron · Sep 1, 2026Peer-reviewedCell Biology

Mitochondria-containing large extracellular vesicles target mouse motor neurons upon intramuscular injection

Paromita Paul Pinky, Zhong-Min Wang, Purva Khare, Jhanvi R Jhaveri, Abigail Sullivan, Vivek Basudkar, Krithika Rao, Audrey Lawrence, Adithri Pingali, Kandarp M. Dave, Donna Beer Stolz, Ming Sun, Si-yang Zheng, Sruti S. Shiva, Carol Milligan, , Devika Soundara Manickam

This study shows that mitochondria-containing large extracellular vesicles (lEVs) improve mitochondrial function in heat-stressed neurons and deliver mitochondria to motor neurons in vivo.

Extracellular Vesicle · Dec 24, 2025Peer-reviewedBioengineering

Ionic liquid-coated lipid nanoparticles demonstrate prolonged circulation and brain uptake via red blood cell hitchhiking

Purva Khare, Sara X. Edgecomb, Christine M. Hamadani, Duoyi Hu, Balaji Govindaswamy, George R. Taylor, Rocco Caprara, Eden E. L. Tanner, Devika Soundara Manickam

This study shows that ionic liquid-coated lipid nanoparticles can hitchhike on red blood cells, improving brain uptake and circulation time compared to uncoated nanoparticles.

Journal of Controlled Release · Nov 30, 2025Peer-reviewedBioengineering