Donna Beer Stolz

The paper compares sequential centrifugation and density gradient centrifugation for isolating mitochondria-containing large extracellular vesicles.

This study shows that mitochondria-containing large extracellular vesicles (lEVs) improve mitochondrial function in heat-stressed neurons and deliver mitochondria to motor neurons in vivo.

The paper identifies NCOA7's role in lysosomal function and inflammatory sterol metabolism in PAH, showing its deficiency exacerbates disease through oxysterol/bile acid generation.

This study creates a human iPSC-derived hepatocyte model with the TM6SF2 E167K mutation to study its effects on lipid metabolism and MASLD.

This study compares the therapeutic efficacy of mitochondria-containing extracellular vesicles from mouse and human brain endothelial cells in a mouse stroke model, finding that mouse-derived vesicles are more effective.

The paper introduces iDiscoid, a human stem cell model of post-implantation development that recapitulates key morphogenetic features and offers a platform for studying early human development.

This study identifies a reduction in ER chaperones in PWS β-cells, leading to impaired insulin secretion and ER stress.

This paper identifies chd-7's role in collagen regulation in nematodes and vertebrates, linking it to CHARGE syndrome features through extracellular matrix misregulation.

The paper shows myosin 1d is essential for establishing left-right asymmetry in zebrafish through actin-myosin driven chirality.