Qi Chen

Grass Expression Atlas: an RNA-seq-based expression resource for grass species.

Grass Expression Atlas provides an RNA-seq-based resource for gene expression across diverse grass species and conditions.

Ribophorin-1 Governs Spike Abundance of Highly Pathogenic Coronaviruses by ER-associated degradation

This study identifies Ribophorin-1 as a host factor that reduces spike protein abundance on coronaviruses by promoting its degradation, thereby inhibiting infection.

NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages drive chemoradiotherapy resistance in esophageal squamous cell carcinoma

This study identifies NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages as drivers of chemoradiotherapy resistance in ESCC through multi-omics analysis of clinical trial data.

Characterization of RNA interference in the model cnidarian Nematostella vectensis reveals partial target silencing but lack of small RNA amplification

This study investigates RNA interference in Nematostella vectensis, showing siRNA generation and partial target silencing but no secondary siRNA amplification.

CD33KO-CD33-mesothelin loop CAR design avoids fratricide and improves efficacy of iNK cells against acute myeloid leukemia

This study designs a CD33-mesothelin loop CAR to enhance iNK cell efficacy against AML by avoiding fratricide and improving cytotoxicity.

ZNF191 Inhibits Hepatocellular Carcinoma Metastasis via DLG1-mediated YAP1 Inactivation

The paper identifies ZNF191 as a metastasis suppressor in hepatocellular carcinoma by inhibiting YAP1 signaling through DLG1.