Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewed
CD33KO-CD33-mesothelin loop CAR design avoids fratricide and improves efficacy of iNK cells against acute myeloid leukemia
Yao Wang, Xiujuan Zheng, Zhiqian Wang…·Jinyong Wang
This study designs a CD33-mesothelin loop CAR to enhance iNK cell efficacy against AML by avoiding fratricide and improving cytotoxicity.