Author

Weiwei Chen

Affiliated Hospital of Nantong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Animal Behavior & Cognition· 1 Cancer Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anton Sirota· 1 shared Antonio Fernández‐RuiziD· 1 shared Azahara OlivaiD· 1 shared Dashan AiiD· 1 shared Eduardo Blanco-Hernández· 1 shared Emily Naylor· 1 shared Fei DingiD· 1 shared Han LiangiD· 1 shared

Activity by Year

2017-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperAnimal Behavior & Cognition

Anton Sirota

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Destabilization of intratumor Tregs by CTLA-4 engagement confers anti-CTLA-4-driven immunotherapy

Na Liu, Junji Xu, Wai Lim Ku, Weiwei Chen, Yaqiang Cao, Rida Kazmi, Wenwen Jin, Thierry Gauthier, Shunqun Luo, Song Shen, Liliana Catherine Patiño, Yun-Ji Lim, Valentina Ottaviani, Emily Naylor, Keji Zhao, WanJun Chen

This paper shows that anti-CTLA-4 antibodies destabilize intratumor Tregs via TGF-β signaling, enhancing anti-tumor immunity and immunotherapy.

bioRxiv · Aug 1, 2026 · PreprintImmunology

Dynamic shifts in brain criticality support cognitive processing

Hongyu Chang, Weiwei Chen, Lindsay A. Karaba, Xiyu Mei, Ryan E. Harvey, Wenbo Tang, Antonio Fernández‐Ruiz, Azahara Oliva

This study examines how critical dynamics in the hippocampus shift during learning and sleep to support cognitive functions.

bioRxiv · Mar 14, 2026 · PreprintNeuroscience

NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages drive chemoradiotherapy resistance in esophageal squamous cell carcinoma

Jiaying Deng, Zhenzhen Xun, Hu Chen, Yanhong Cen, Yikai Luo, Wei Liu, Weiwei Chen, Junqiang Chen, Jinjun Ye, Xiansu Gao, Qingsong Fan, Jibin Song, Qi Chen, Yuan Li, Fei Ding, , Han Liang

This study identifies NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages as drivers of chemoradiotherapy resistance in ESCC through multi-omics analysis of clinical trial data.

bioRxiv · Feb 21, 2026 · PreprintCancer Biology

Virtual Reality system for freely-moving rodents.

Nicholas A. Del Grosso, Justin J. Graboski, Weiwei Chen, Eduardo Blanco-Hernández, Anton Sirota

This paper introduces a VR system for freely-moving rodents that provides realistic visual feedback to head movements, enabling naturalistic behavior and new experiments on sensory-motor interactions.

bioRxiv · Jul 10, 2017 · PreprintAnimal Behavior & Cognition