Author

Qingru Hua

Peking University

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Biology Disciplines

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Genomics· 1

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Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Chuan CaoiD· 1 shared Cuiting Zhong· 1 shared Guoqing LiuiD· 1 shared Haiguang LiuiD· 1 shared Haitao HuangiD· 1 shared Liu SiD· 1 shared Mingqian Ma· 1 shared Mo Xu· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperGenomics

Chuan CaoORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJul 17, 2026

Reconstructing sequence-grammar trajectories enables interpretable and tunable cis-regulatory element design

Mingqian Ma, Wanjuan Bu, Guoqing Liu…·Zeyu Chen

This paper introduces GO-CRE, a method for designing cell-type-specific cis-regulatory elements by reconstructing sequence-grammar trajectories and using reinforcement learning with predictor guidance.

DOI 10.64898/2026.07.10.737719

humanDNA methylation

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