Cancer BiologybioRxiv
A heterozygous CEBPA mutation disrupting the bZIP domain causes MDS disease progression
R. Almaghrabi, Y. Alyayhawi, P. Keane…·P. Garcia
This study shows a heterozygous CEBPA mutation in the bZIP domain causes MDS progression by altering chromatin structure and clonal composition, using patient-derived iPSCs.