Author

R. Canals

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:gene regulatory network inference· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

J. C. D. Hinton· 5 shared N. Wenner· 4 shared S. V. Owen· 4 shared C. Kröger· 3 shared M. A. Gordon· 3 shared A. V. Predeus· 2 shared D. L. Hammarlöf· 2 shared L. Lacharme-Lora· 2 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

J. C. D. Hinton

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Author profile →

6 papers

Recent·Most cited

Genome-wide fitness analysis identifies genes required for in vitro growth and macrophage infection by African and Global Epidemic pathovariants of Salmonella Enteritidis

W. Y. Fong, R. Canals, A. V. Predeus, B. Perez-Sepulveda, N. Wenner, L. Lacharme-Lora, N. Feasey, P. Wigley, J. C. D. Hinton

This study uses transposon insertion sequencing to identify genes required for growth and macrophage infection in African and Global Epidemic S. Enteritidis, finding shared and strain-specific virulence factors.

bioRxiv · Apr 6, 2022Microbiology

A window into lysogeny: Revealing temperate phage biology with transcriptomics

S. V. Owen, R. Canals, N. Wenner, D. L. Hammarlöf, C. Kröger, J. C. D. Hinton

The paper uses bacterial RNA-seq data to identify novel prophage accessory loci by analyzing transcriptional landscapes of Salmonella prophages.

bioRxiv · Sep 30, 2019Microbiology

African Salmonella Typhimurium sequence type 313 lineage 2 evades MAIT cell recognition by overexpressing RibB

L. Preciado-Llanes, A. Aulicino, R. Canals, P. Moynihan, X. Zhu, N. Jambo, T. Nyirenda, I. Kadwala, S. V. Owen, N. Veerapen, G. S. Besra, M. A. Gordon, J. C. D. Hinton, G. Napolitani, M. Salio, A. Simmons

The paper shows African S. Typhimurium lineage 2 strains evade MAIT cell recognition by overexpressing ribB, which may contribute to their pathogenicity.

bioRxiv · Sep 10, 2019Immunology

The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid

R. Canals, R. R. Chaudhuri, R. E. Steiner, S. V. Owen, N. Quinones-Olvera, M. A. Gordon, M. Ibba, J. C. D. Hinton

The paper uses transposon insertion sequencing to analyze the fitness landscape of Salmonella Typhimurium ST313 strain D23580, identifying essential genes and plasmid-encoded factors affecting growth and macrophage infection.

bioRxiv · Jul 1, 2019Microbiology

The diversity, evolution and ecology of Salmonella in venomous snakes

C. V. Pulford, N. Wenner, M. L. Redway, E. V. Rodwell, H. J. Webster, R. Escudero, C. Kröger, R. Canals, W. Rowe, J. Lopez, N. Hall, P. D. Rowley, D. Timofte, R. A. Harrison, K. S. Baker, J. C. D. Hinton

This study investigates Salmonella diversity in venomous snakes, finding 91% prevalence and identifying metabolic differences between subspecies, suggesting a potential role in human Salmonellosis in Africa.

bioRxiv · Jan 21, 2019Microbiology

Adding function to the genome of African Salmonella ST313

R. Canals, D. L. Hammarlöf, C. Kröger, S. V. Owen, W. Y. Fong, L. Lacharme-Lora, X. Zhu, N. Wenner, S. E. Carden, J. Honeycutt, D. M. Monack, R. A. Kingsley, P. Brownridge, R. R. Chaudhuri, W. P. M. Rowe, , J. Hinton

The paper compares genomic and transcriptomic differences between Salmonella ST313 and ST19 isolates to identify phenotypic variations and a novel plasmid maintenance system.

bioRxiv · Oct 22, 2018Microbiology