Proximal and Distal Nephron-specific Adaptation to Furosemide
A. J. Krauson, S. Schaffert, E. M. Walczak, J. M. Nizar, G. M. Holdgate, S. Iyer, R. Elsayed, A. Gaudet, P. Khatri, V. Bhalla
This study investigates how furosemide induces distinct adaptive responses in proximal and distal nephron segments, revealing mechanisms of diuretic resistance and tubular remodeling.
bioRxiv · Jan 12, 2021 · PreprintPhysiology