Author

R. Esterberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Saint-Geniez· 3 shared Y. Xu· 3 shared J. Demirs· 2 shared K. Bond· 2 shared M. Twarog· 2 shared Q. Huang· 2 shared Y. Bao· 2 shared C. Hayden· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

M. Saint-Geniez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

APOE Impacts Lipid Trafficking in Retinal Pigment Epithelium Cells

S. E. Richards, J. Demirs, S. Jose, L. Fan, Y. Xu, R. Esterberg, C.-L. Huang, C. W. Wilson, M. Saint-Geniez, S.-M. Liao

This study investigates how APOE variants affect lipid trafficking in RPE cells, finding that APOE knockout and APOE2-expressing cells show lipid transport deficits, while APOE4-expressing cells upregulate APOE in response to lipid challenges.

bioRxiv · May 30, 2024 · PreprintCell Biology

Protective effect of P2Y receptors antagonism on stress-induced retinal degeneration

Y. Bao, K. Bond, P. Sarraf, R. Esterberg, M. Serpa, M. Twarog, Y. Xu, H. MacLeod, Q. Huang, M. Saint-Geniez

This study shows that blocking P2Y receptors with suramin prevents stress-induced RPE and photoreceptor degeneration in vitro and in a zebrafish model.

bioRxiv · May 28, 2024 · PreprintCell Biology

Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation

G. Klokman, Y. Xu, K. Bond, X. Wu, J. Schustak, J. Mandelbaum, M. Twarog, H. Han, M.-K. Paulina, M. Coble, C. Hayden, J.-R. Galarneau, J. Demirs, Y. Qiu, R. Esterberg, , Y. Bao

This study shows dsRNA triggers RIG-I signaling, leading to inflammation and RPE degeneration in AMD, with implications for pathogenesis.

bioRxiv · Mar 11, 2024 · PreprintCell Biology