R. Grima

Exact solution of a three-stage model of stochastic gene expression including cell-cycle dynamics

This paper derives an exact solution for a three-stage stochastic gene expression model that includes cell-cycle dynamics, showing discrepancies with the classical model that ignores cell-cycle effects.

Steady-state distributions of nascent RNA for general initiation mechanisms

The paper derives an exact relationship between steady-state nascent RNA distributions and initiation time distributions, validated through simulations and live cell imaging.

A stochastic model of corneal epithelium maintenance and recovery following perturbation

This paper develops a stochastic model to study corneal epithelium maintenance and recovery, identifying key factors and noise reduction mechanisms in homeostasis.