The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport
H. Bustamante, K. Cereceda, A. Gonzalez, G. Valenzuela, Y. Cheuquemilla, S. Hernandez, E. Arias, C. Cerda-Troncoso, S. Bandau, A. Soza, G. Kausel, B. Kerr, G. Mardones, J. Cancino, R. Hay, , P. Burgos
The paper identifies PSMD14 as a regulator of Golgi-to-ER retrograde transport and macroautophagy through its role in K63-Ub chain deubiquitination.
bioRxiv · Jan 29, 2020Cell Biology