The role of high cholesterol in age related COVID19 lethality.
H. Wang, Z. Yuan, M. A. Pavel, S. M. Jablonski, J. Jablonski, R. Hobson, S. Valente, C. B. Reddy, S. Hansen
This study shows high cholesterol enhances SARS-CoV-2 entry and infectivity by promoting ACE2 and furin localization, contributing to COVID19 severity in elderly and obese individuals.
bioRxiv · May 9, 2020Cell Biology