MicrobiologybioRxiv
A label-free approach for relative spatial quantitation of c-di-GMP in microbial biofilms
C. McCaughey, M. Trebino, A. McAtamney…·L. Sanchez
This study develops a label-free method to detect spatial changes in c-di-GMP levels in microbial biofilms using MALDI-MSI and applies it to three bacterial species.
DOI 10.1021/acs.analchem.3c04687