Author

R. Juehlen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Fahrenkrog· 2 shared V. Martinelli· 2 shared A. Dickmanns· 1 shared A. Filosa· 1 shared A. Mendes· 1 shared B. Vanhollebeke· 1 shared C. Spillner· 1 shared E. Bonnin· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

B. Fahrenkrog

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Author profile →

2 papers

Recent·Most cited

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements

A. Mendes, R. Juehlen, V. Martinelli, B. Fahrenkrog

This study shows that CRM1 inhibition disrupts NUP214 fusion proteins in leukemia cell lines, leading to anti-cancer effects by altering nuclear localization and cell viability.

bioRxiv · Apr 23, 2020Cancer Biology

Mutations in nucleoporin NUP88 cause lethal neuromuscular disorder

E. Bonnin, P. Cabochette, A. Filosa, R. Juehlen, S. Komatsuzaki, M. Hezwani, A. Dickmanns, V. Martinelli, M. Vermeersch, L. Supply, N. Martins, L. Pirenne, G. Ravenscroft, M. Lombard, S. A. Port, , B. Fahrenkrog

This study identifies biallelic NUP88 mutations as a cause of lethal fetal akinesia deformation sequence (FADS) and shows their effects on neuromuscular development in zebrafish and human cells.

bioRxiv · Aug 14, 2018Cell Biology