Author

A. Mendes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:drug response / drug discovery· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

C. Almeida· 2 shared D. Barros· 2 shared E. Gatti· 2 shared P. Pierre· 2 shared R. J. Argüello· 2 shared A. Galy· 1 shared A. W. Paton· 1 shared A.-M. Lennon-Dumenil· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

C. Almeida

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

VPS34-IN1 inhibits cap-mediated translation and synergizes with STING to drive type-I IFN expression in human plasmacytoid DCs

P. Antas, M. Machado, F. Pinheiro, D. Barros, C. Ramalhinho, A. Mendes, B. Ferreira, D. Carvoeiro, M. Reverendo, I. F. Duarte, M. Narita, B. Su, R. J. Argüello, B. Nal Rogier, P. Pierre, , E. Gatti

VPS34-IN1 inhibits cap-mediated translation and enhances STING-driven type-I IFN expression in human plasmacytoid DCs by altering SGK3 recruitment and STING degradation.

bioRxiv · Jun 17, 2024Immunology

Mannose-coupled AAV2: a second generation AAV vector for increased retinal gene therapy efficiency

M. MEVEL, V. Pichard, M. Bouzelha, D. Alvarez-Dorta, P.-A. Lalys, N. Provost, M. Allais, A. Mendes, E. Landagaray, J.-B. Ducloyer, A. Galy, N. Brument, G. M. Lefevre, S. G. Gouin, C. Isiegas, , O. Adjali

This study develops a modified AAV vector with increased transduction efficiency in retinas of rats and nonhuman primates by covalently attaching mannose ligands.

bioRxiv · Dec 1, 2022Bioengineering

Sensory neuron-associated macrophages proliferate in the sensory ganglia after peripheral nerve injury in a CX3CR1 signaling dependent manner

R. M. Guimaraes, E. A. Silva, M. Davoli-Ferreira, F. I. F. Gomes, A. Mendes, M. Fonseca, S. Damasceno, L. P. Andrade, F. Q. Cunha, J. C. Alves-Filho, T. M. Cunha

This study shows that sensory neuron-associated macrophages proliferate in the sensory ganglia after nerve injury, driven by CX3CR1 signaling, and contribute to inflammation.

bioRxiv · Mar 22, 2022Immunology

Developmentally regulated PERK activity renders dendritic cells insensitive to subtilase cytotoxin-induced integrated stress response

P. Pierre, A. Mendes, J. P. Gigan, C. Rodriguez Rodrigues, S. A. Choteau, D. Sanseau, D. Barros, C. Almeida, V. Camosseto, L. Chasson, A. W. Paton, J. C. Paton, R. J. Argüello, A.-M. Lennon-Dumenil, E. Gatti

The paper shows dendritic cells have high eIF2 phosphorylation due to PERK activation, but this does not lead to chronic ISR or translation arrest, allowing them to adapt to stress.

bioRxiv · Apr 27, 2020 · PreprintImmunology

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements

A. Mendes, R. Juehlen, V. Martinelli, B. Fahrenkrog

This study shows that CRM1 inhibition disrupts NUP214 fusion proteins in leukemia cell lines, leading to anti-cancer effects by altering nuclear localization and cell viability.

bioRxiv · Apr 23, 2020Cancer Biology