Androgens at the skin surface regulate S. aureus pathogenesis through the activation of agr quorum sensing
Maria Sindhura John, Mahendran Chinnappan, Methinee Artami, M. Bhattacharya, R. Keogh, J. Kavanaugh, T. Sharma, Alexander R. Horswill, Tamia A. Harris-Tryon
This study shows that androgens like testosterone promote S. aureus pathogenesis by activating the agr quorum sensing system, leading to increased virulence and skin infection.
Journal of Investigative Dermatology · Jul 19, 2024Peer-reviewedMicrobiology