PhysiologybioRxiv
The bitter end: T2R bitter receptor agonists elevate nuclear calcium and induce apoptosis in non-ciliated airway epithelial cells
D. B. McMahon, L. E. Kuek, M. E. Johnson…·R. J. Lee
This study shows T2R agonists induce apoptosis in non-ciliated airway cells through nuclear calcium and mitochondrial pathways, potentially as a defense against infection or a risk in disease.
DOI 10.1016/j.ceca.2021.102499