MicrobiologybioRxiv
Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection
R. L. Kruse, X. Legras, M. Barzi
This paper develops recombinant circular HBV genomes (rcccDNA) using Cre/LoxP technology to better model cccDNA for HBV therapy research.
DOI 10.1016/j.virusres.2020.198224