Attenuation hotspots in neurotropic human astroviruses
H. Ali, A. Lulla, A. S. Nicholson, E. B. Wignall-Fleming, R. L. OConnor, D.-L. Vu, S. C. Graham, J. E. Deane, S. Guix, V. Lulla
This study identifies attenuation hotspots in neurotropic human astroviruses by analyzing dispensable regions in the capsid-coding region and confirms their role in neuronal attenuation using recombinant viruses.
bioRxiv · Sep 6, 2022Microbiology