ImmunologybioRxiv
A comparison of the binding sites of antibodies and single-domain antibodies
G. L. Gordon, H. L. Capel, B. Guloglu…·C. M. Deane
This study compares the binding sites of antibodies and single-domain antibodies, showing they target similar epitope sizes and shapes but differ in paratope interactions and framework residue importance.
DOI 10.3389/fimmu.2023.1231623