Cancer BiologybioRxivPreprint
HDAC1 regulates the chromatin landscape to establish transcriptional dependencies in chronic lymphocytic leukemia
T.-h. Lai, H. G. Ozer, P. Gasparini…·D. Sampath
This study identifies HDAC1's role in establishing transcriptional dependencies in CLL by analyzing chromatin features and shows HDAC1 inhibition disrupts B-cell signaling and survival networks.