ImmunologybioRxivPreprint
Human NLRP1 is activated by ZAKa-driven ribotoxic stress response
K. S. ROBINSON, G. A. TOH, P. ROZARIO…·F. L. Zhong
This paper identifies ZAKa-driven ribotoxic stress as a mechanism for activating human NLRP1, leading to pyroptosis in response to UVB and microbial ribotoxins.
DOI 10.1101/2022.01.24.477516