Author

R. P. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

R. J. Wilkinson· 3 shared M. G. Gutierrez· 2 shared S. Marais· 2 shared A. Fearns· 1 shared A. Garza-Garcia· 1 shared A. O'Garra· 1 shared C. J. Queval· 1 shared D. B. Young· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

R. J. Wilkinson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transcriptomic characterization of tuberculous sputum reveals a host Warburg effect and microbial cholesterol catabolism

R. P. Lai, T. Cortes, S. Marais, N. Rockwood, M. L. Burke, A. Garza-Garcia, S. Horswell, A. O'Garra, D. B. Young, R. J. Wilkinson

This study uses RNA-sequencing on TB sputum to reveal host metabolic shifts and microbial cholesterol catabolism during tuberculosis transmission.

bioRxiv · Mar 9, 2020Microbiology

Elevated LRRK2 and α-synuclein levels in CSF of infectious meningitis patients

S. Herbst, S. Marais, M. G. Gutierrez, S. J. Waddell, R. J. Wilkinson, R. P. Lai

The paper finds elevated levels of LRRK2 and α-synuclein in CSF of infectious meningitis patients, suggesting a link between neuroinflammation and infection.

bioRxiv · Apr 4, 2019 · PreprintImmunology

Mycobacterium tuberculosis cording in the cytosol of live lymphatic endothelial cells

T. R. Lerner, C. J. Queval, R. P. Lai, M. R. G. Russell, A. Fearns, D. J. Greenwood, L. Collinson, R. J. Wilkinson, M. G. Gutierrez

This study shows that Mycobacterium tuberculosis forms intracellular cords in human lymphatic endothelial cells, evading xenophagy via the ESX-1 system and PDIM lipid.

bioRxiv · Apr 1, 2019 · PreprintCell Biology