Role of Delta-Notch signalling molecules on cell-cell adhesion in determining heterogeneous chemical and cell morphological patterning
S. Bajpai, R. Chelakkot, R. Prabhakar, M. M. Inamdar
This study extends a vertex model of epithelial tissues to include contact-dependent signaling and mechanochemical coupling, showing that two-way interactions between cell mechanics and signaling can produce diverse patterns in cell size and shape.
bioRxiv · Feb 25, 2022Biophysics