Author

R. Pye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:non-human primate· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. Flies· 2 shared J. Darby· 2 shared K. Swift· 2 shared S. Fox· 2 shared A. B. Lyons· 1 shared A. Baez-Ortega· 1 shared A. Flies· 1 shared A. T. Gilbert· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

A. S. Flies

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Automated analysis of PD1 and PDL1 in lymph nodes and the microenvironment of transmissible tumors in Tasmanian devils

G. G. Russell, C. Palmieri, J. Darby, G. P. Morris, N. M. Fountain-Jones, R. Pye, A. S. Flies

This study uses QuPath to analyze PD1 and PDL1 expression in Tasmanian devil lymph nodes, finding higher PD1 expression in germinal centers and increased PD1-positive cells in DFT2 metastases.

bioRxiv · Oct 31, 2022Immunology

The evolution of two transmissible cancers in Tasmanian devils

M. R. Stammnitz, K. Gori, Y. M. Kwon, E. Harry, F. J. Martin, K. Billis, Y. Cheng, A. Baez-Ortega, W. Chow, S. Comte, H. Eggertsson, S. Fox, R. Hamede, M. E. Jones, B. Lazenby, , E. P. Murchison

This study analyzes the genetic diversity and evolution of two transmissible cancers in Tasmanian devils, revealing their emergence dates, mutation rates, and evolutionary patterns.

bioRxiv · May 27, 2022Cancer Biology

Ethyl-Iophenoxic acid as a serum marker for oral baiting of carnivorous marsupials

R. Pye, D. S. Nichols, A. T. Gilbert, A. S. Flies

This study tests Et-IPA as a biomarker for oral bait consumption in Tasmanian devils, finding it remains detectable in serum for at least 56 days.

bioRxiv · Dec 14, 2021 · PreprintZoology

Post release immune responses of Tasmanian devils vaccinated with an experimental devil facial tumour disease vaccine

R. Pye, J. Darby, A. Flies, S. Fox, S. Carver, J. Elmer, K. Swift, C. Hogg, D. Pemberton, G. Woods, A. B. Lyons

This study evaluates the immune response of Tasmanian devils vaccinated against DFTD, finding persistent antibodies and immune cell infiltration in tumors, but no complete protection against DFTD development.

bioRxiv · Dec 6, 2020Immunology